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  • Solutions
    • By route of deliveryOral, Nasal, Pulmonary & Parenteral
          • By route of delivery

          • OralTablets, capsules, powders and granules
          • NasalSprays, suspensions and dry powders
          • Nose-to-brain / CNS DeliveryDirect nasal routes for CNS programmes
          • Pulmonary & InhalationDry powder and inhaled dosage forms
          • Parenteral, Aseptic & Fill-FinishSterile vials and aseptic processing
          • Not sure where to start?

            Tell us the molecule and the stage.

            Every enquiry goes to a formulation scientist.

            Start a project →
    • By stage & servicePre-clinical to market
          • By stage & service

          • Formulation DevelopmentBioavailability, Solubility, Target Profile
          • Analytical Development & ValidationMethod development, transfer and stability
          • Phase I - II Clinical SupplyGMP batches for early clinical studies
          • Process Scale-Up for Phase IIIBench to commercial scale transfer
          • Regulatory Affairs SupportCMC documentation and submissions
          • Not sure where to start?

            Tell us the molecule and the stage.

            Every enquiry goes to a formulation scientist.

            Start a project →
    • Platforms & TechnologyOur proprietary toolkit
          • Platforms & Technology

          • Spray DryingOur core enabling technology
          • UpperNose TMNasal delivery platform
          • PulmoCraft TMEngineered particles for inhalation
          • UpperSolv TMSolubility enhancement
          • Spray-Dried BiologicsProteins, peptides and monoclonal antibodies
          • Not sure where to start?

            Tell us the molecule and the stage.

            Every enquiry goes to a formulation scientist.

            Start a project →
    • Complex & Controlled MoleculesSpecialist potency handling
          • Complex & Controlled Molecules

          • High-Potency APIs & ContainmentContained handling in dedicated suites
          • Controlled Substances ManufacturingLicensed facility for scheduled substances
          • Psychedelics & Novel CNSFormulation and supply for emerging CNS work
          • Not sure where to start?

            Tell us the molecule and the stage.

            Every enquiry goes to a formulation scientist.

            Start a project →
  • Choose Upperton
        • A CDMO partner that steps up where others turn away

          Expertise across oral, nasal, pulmonary and parenteral dosage forms

        • Selecting Your CDMO PartnerWhy choose us
        • Quality & ComplianceMHRA and FDA inspected, GMP throughout
        • Our Project Management ApproachOne team, from start to finish
        • Case Studies & Track RecordProgrammes we have taken to market
        • Case studies

          Rapid tech transfer to clinical manufacture

          Read how we reached clinical dosing within three months, through strong communication, flexibility and responsiveness.

          Read the case study →
  • About us
        • About Upperton

        • FacilitiesTrent Gateway, Nottingham
        • Our PeopleLeadership, board and subject matter experts
        • EventsWhere to meet us
        • Company OverviewWho we are and what we do
        • CareersWorking at Upperton
        • ESGEnvironmental, social and governance
        • Awards & AchievementsAward-winning CDMO
        • Working here

          Scientists, not a form queue.

          Open roles across formulation, analytical and operations.

          See open roles →
  • Resources
        • One library. Filter it your way.

          Search across everything, then narrow by route, platform, service or stage.

        • Popular filters

        • Spray drying
        • Inhalation
        • Biologics
        • Solubility
        • Phase I-II
        • Sterile fill-finish
        • Browse by type

        • Articles & InsightsTechnical articles from our scientists
        • Whitepapers & InfosheetsIn-depth technical documents
        • BrochuresCapability and facility overviews
        • Webinars & Scientific PostersRecorded sessions and conference posters
        • Media / Press KitLogos, imagery and press contacts
        • FAQCommon questions on process and supply
        • Featured whitepaper

          Spray drying biologics: an alternative to freeze drying.

          Dr Richard Johnson, Chief Scientific Officer.

          Download →
  • Contact
        • One enquiry form. Tell us the stage and it routes itself.

          No separate proposal request, no separate discovery call booking.

        • What stage is your project?

        • Early / exploratory
        • Pre-clinical
        • Phase I-II
        • Phase III+
        • Commercial
        • Get in touch

          Call +44 (0) 115 855 7050
          Email contact@upperton.com
          Visit Trent Gateway, Technology Drive, Beeston, Nottingham, NG9 1LA

        • Start a project

          Send us the brief and we will reply within one working day.

          Answered by a scientist who works on your route.

          Open the form →

Service Area: Manufacturing

Inhalation Drug Product Development and Manufacturing: Information Sheet

Intranasal Drug Product Development and Manufacturing

Webinar: Scaling Up Oral Solid Dose Manufacturing for Late-Phase Success

Does a One-Site CDMO Make a Difference in Drug Development?

A one-site CDMO is where GMP, R&D and manufacturing all operate on one site, making the movement of projects streamlined.

Tech Transfer in Late-Stage Oral Solid Dose Projects: Lessons Learnt and Best Practices from a CDMO Perspective

Tech transfer in oral solid dose (OSD) manufacturing is one of the most critical, and often underestimated, phases in the drug development lifecycle. For CDMOs, it’s a moment where scientific precision meets operational discipline.

Upperton Expands High Precision Filling Capability at Nottingham Facility

Upperton has increased its filling capability with the installation of the Fill2Weight gravimetric powder filling machine from 3P innovation

Upperton Pharma Solutions Awarded VaxHub Sustainable Grant to Advance Oral Vaccine Delivery in Partnership with the University of Oxford’s Pandemic Sciences Institute

Upperton will apply its expertise to enable the next generation of Adenovirus-vectored vaccines to be delivered without needles.

Project Management Spotlight with Sophie Skinner

Discover more about our team. In this Spotlight, meet our Project Coordinator, Sophie Skinner, on her journey with Upperton.

Webinar – Navigating the Sterile Fill Finish CDMO Landscape for Development & Manufacturing Success

Nikki Whitfield, CEO of Upperton Pharma Solutions, Honoured with ‘CEO Excellence in Pharmaceutical Manufacturing’ Award at the CEO Today Global Awards 2025.

Nikki Whitfield, CEO of Upperton, has received the ‘CEO Excellence in Pharmaceutical Manufacturing’ Award at the CEO Today Global Awards 2025

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Upperton is a UK-based CDMO delivering drug product development, formulation, clinical manufacturing, and regulatory support for biotech and pharmaceutical companies worldwide.

Get in Touch

Trent Gateway, Technology Drive,
Beeston, Nottingham, NG9 1LA, UK

+44 (0) 115 855 7050

contact@upperton.com

Integrated CDMO services

  • Solutions
    • By route of delivery
      • Oral
      • Nasal
      • Nose-to-brain / CNS Delivery
      • Pulmonary & Inhalation
      • Parenteral, Aseptic & Fill-Finish
    • By stage & service
      • Formulation Development
      • Analytical Development & Validation
      • Phase I – II Clinical Supply
      • Process Scale-Up for Phase III
      • Regulatory Affairs Support
    • Platforms & Technology
      • Spray Drying
      • UpperNose TM
      • PulmoCraft TM
      • UpperSolv TM
      • Spray-Dried Biologics
    • Complex & Controlled Molecules
      • High-Potency APIs & Containment
      • Controlled Substances Manufacturing
      • Psychedelics & Novel CNS
  • Choose Upperton
    • Selecting Your CDMO Partner
    • Quality & Compliance
    • Our Project Management Approach
    • Case Studies & Track Record
  • About us
    • Facilities
    • Our People
    • Events
    • Company Overview
    • Careers
    • ESG
    • Awards & Achievements
  • Resources
    • Articles & Insights
    • Whitepapers & Infosheets
    • Brochures
    • Webinars & Scientific Posters
    • Media / Press Kit
    • FAQ
    • Spray drying
    • Inhalation
    • Biologics
    • Solubility
    • Phase I-II
    • Sterile fill-finish
  • Contact
    • Early / exploratory
    • Pre-clinical
    • Phase I-II
    • Phase III+
    • Commercial
  • Solutions
    • By route of delivery
      • Oral
      • Nasal
      • Nose-to-brain / CNS Delivery
      • Pulmonary & Inhalation
      • Parenteral, Aseptic & Fill-Finish
    • By stage & service
      • Formulation Development
      • Analytical Development & Validation
      • Phase I – II Clinical Supply
      • Process Scale-Up for Phase III
      • Regulatory Affairs Support
    • Platforms & Technology
      • Spray Drying
      • UpperNose TM
      • PulmoCraft TM
      • UpperSolv TM
      • Spray-Dried Biologics
    • Complex & Controlled Molecules
      • High-Potency APIs & Containment
      • Controlled Substances Manufacturing
      • Psychedelics & Novel CNS
  • Choose Upperton
    • Selecting Your CDMO Partner
    • Quality & Compliance
    • Our Project Management Approach
    • Case Studies & Track Record
  • About us
    • Facilities
    • Our People
    • Events
    • Company Overview
    • Careers
    • ESG
    • Awards & Achievements
  • Resources
    • Articles & Insights
    • Whitepapers & Infosheets
    • Brochures
    • Webinars & Scientific Posters
    • Media / Press Kit
    • FAQ
    • Spray drying
    • Inhalation
    • Biologics
    • Solubility
    • Phase I-II
    • Sterile fill-finish
  • Contact
    • Early / exploratory
    • Pre-clinical
    • Phase I-II
    • Phase III+
    • Commercial

By Development Stage

  • Pre-clinical
  • Phase 1 to Phase 2
  • Phase 3 – Commercial
  • Pre-clinical
  • Phase 1 to Phase 2
  • Phase 3 – Commercial

Development Platforms

  • PulmoCraft
  • UpperNose
  • UpperSolv
  • PulmoCraft
  • UpperNose
  • UpperSolv

Route of delivery

  • Oral
  • Nasal
  • Pulmonary
  • Parenteral
  • Oral
  • Nasal
  • Pulmonary
  • Parenteral

About Us

  • About
  • Our Facilities
  • Our History
  • Awards and Achievements
  • Executive Management Team
  • Board of Directors
  • Careers
  • About
  • Our Facilities
  • Our History
  • Awards and Achievements
  • Executive Management Team
  • Board of Directors
  • Careers

Our Approach

  • Project Management
  • Project Management

Events

  • Events & Seminars
  • Events & Seminars

Policies

  • News
  • Insights
  • Webinars
  • Whitepapers
  • Scientific Posters
  • Frequently Asked Questions
  • News
  • Insights
  • Webinars
  • Whitepapers
  • Scientific Posters
  • Frequently Asked Questions

Our Approach

  • Privacy Policy
  • ESG Code of Conduct
  • Criminal Offence Policy
  • Whistleblower Policy
  • Privacy Policy
  • ESG Code of Conduct
  • Criminal Offence Policy
  • Whistleblower Policy