Dry Powder Formulation: The Next Generation
Outlining the Trends and Challenges in the Inhaled Drug Delivery Market, with a Special Focus on Dry Powder Formulation.
Successful Scale-Up of a Spray Dried Formulation for Nasal Drug Delivery
Upperton Joined by Professor Dame Sarah Gilbert, To Officially Open New Development and GMP Manufacturing Facility.
Upperton Joined by Professor Dame Sarah Gilbert, To Officially Open New Development and GMP Manufacturing Facility.
Upperton completes build of new £15m development and GMP manufacturing facility
Leading UK contract development and manufacturing organisation (CDMO), Upperton Pharma Solutions has completed the build of its new development and GMP manufacturing headquarters in Nottingham, UK. Situated less than two miles from Upperton’s current HQ, the facility ‘Trent Gateway’ houses ten new GMP manufacturing suites, quality control laboratories and formulation development with pilot plant capabilities. […]
Nasal Inhalation Delivery – An Introduction Guide
An introduction to nasal delivery The delivery of APIs via nasal inhalation is of growing interest to companies looking to exploit the benefits of this delivery route. Delivery targets are typically broken down into three categories Local delivery to the nasal membranes (e.g. for vaccines, antivirals, prophylactics) Systemic delivery by absorption into the bloodstream (e.g. […]
Nasally Delivered Dry Powder Dosage Forms: Particle Size Analysis
Introduction to Nasal Delivery The delivery of APIs via nasal inhalation is of growing interest to companies looking to exploit the benefits of this delivery route. Delivery targets are typically broken down into three categories Local delivery to the nasal membranes (e.g. for vaccines, antivirals, prophylactics) Systemic delivery by absorption into the bloodstream (e.g. for […]
Upperton’s new Nottingham facility
18th January 2023 Upperton Pharma Solutions, a leading UK contract development and manufacturing organisation (CDMO), is delighted to announce that it has begun construction work for its new Development and GMP Manufacturing headquarters in Nottingham, UK. Working in close collaboration with its principal Design and Build contractor, T-SQUARED the team officially broke ground on the […]
Build of New Development and Manufacturing Facility
29th November 2022 – Press Release & Newsletter Upperton Pharma Solutions Appoints T-SQUARED for Design and Build of New Development and Manufacturing Facility Upperton Pharma Solutions, a leading UK contract development and manufacturing organisation (CDMO), is delighted to announce that it has appointed T-SQUARED, UK based company, as the principal Design and Build contractor for […]
Upperton Launches ASAPprime® Shelf-Life Stability Testing
November 16th 2022 : Newsletter Upperton has made a significant investment in ASAPprime® software and hardware to enable the company to offer its clients state of the art stability testing. This exciting new platform can be used to generate robust, accelerated chemical stability data and is now being applied at all stages of the product […]
In Vitro Testing of Dry Powder Nasal Delivery Devices
Successful nasal drug delivery of dry powder formulations requires a delivered dose that can penetrate beyond the nasal entrance region and deposit in the peripheral nasal cavity, whilst avoiding deeper penetration to the airways of the lungs. This delivery, or deposition pattern, is determined by the aerodynamic particle size of the powder exiting the device, […]