Applications and Techniques of Pharmaceutical Granulation
What is Granulation? Wet Granulation Wet Granulation Options Dry Granulation Dry Granulation Options Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour What is Granulation? Granulation has been widely used in the pharmaceutical industry since the 1950s. Whilst the science remains largely identical to that developed over 70 years […]
Tablet Formulation: A General Overview
Tablet Formulation Strategies Solid Dosage Forms Tablet Manufacture Process Tablet Press FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour Tablets continue to be one of the most popular pharmaceutical dosage forms, as with the right tablet formulation you can achieve: ease of handling and administration for patients, […]
Tablets: A General Overview
Listen to the article Loading the Elevenlabs Text to Speech AudioNative Player… What are Oral Solid Tablets? Examples of Tablets Considerations for Tablet Design FAQs Tablet dosage forms are one of the most popular dosage forms used in the pharmaceutical industry due to their ease of handling and administration for patients, stability, convenient packing options […]
Oral Solid Dosage Forms Containing Amorphous Spray Dried Dispersions: Choices for First in Human Studies
The number of amorphous solid dispersions entering first in human (FIH) studies continues to increase, due to the growing number of novel APIs with a poor solubility profile, and associated bioavailability challenges. Spray drying is a useful technology for creating a form of amorphous solid dispersions called spray dried dispersions (SDDs). Spray drying a poorly […]
Assessing Bioavailability Enabling Technologies using Upperton Pharma Solutions Screening Platform – UpperSolv™+
Currently approximately 9 out of 10 new drugs entering clinical trials will fail before reaching approval. Many of these drugs will fail due to problems with ADME (absorption, distribution, metabolism and excretion) rather than lack of efficacy. One of the more common issues associated with ADME is the need for increasing bioavailability. Therefore, it is […]
Upperton continues to invest in key equipment to support expansion of its solid dosage form capabilities and CDMO Services
29th October 2019 – Press Release Upperton Pharma Solutions, a UK-based contract development and manufacturing organisation (CDMO) has significantly increased its solid dosage form capabilities following a strategic investment in a new state-of the-art tablet coater. This investment will enhance the company’s development and manufacturing capabilities whilst strengthening their ability to support clients’ research, development […]
Upperton Pharma Solutions Investment Increases Tabletting Capabilities
17th September 2019 – Press Release In recent weeks Upperton has been focussing heavily on enhancing our formulation capabilities (through increased tabletting capabilities) with a series of investments in new equipment for our R&D and QC laboratories. This is now being followed by our largest ever capital investment programme aimed at bringing in new manufacturing […]
Developing Oral Dosage Forms for Clinical Trials – Tablets vs Capsules
Dosage Form Selection Designing a Process for Tablet Manufacture Designing a Process for Capsule Manufacture FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Dosage Form Selection Producing a spray dried powder is rarely the end of developing an oral dosage form pathway. Further processing is usually required in order to create a oral dosage […]