Nasally Delivered Dry Powder Dosage Forms: Particle Size Analysis
Introduction to Nasal Delivery The delivery of APIs via nasal inhalation is of growing interest to companies looking to exploit the benefits of this delivery route. Delivery targets are typically broken down into three categories Local delivery to the nasal membranes (e.g. for vaccines, antivirals, prophylactics) Systemic delivery by absorption into the bloodstream (e.g. for […]
In Vitro Testing of Dry Powder Nasal Delivery Devices
Successful nasal drug delivery of dry powder formulations requires a delivered dose that can penetrate beyond the nasal entrance region and deposit in the peripheral nasal cavity, whilst avoiding deeper penetration to the airways of the lungs. This delivery, or deposition pattern, is determined by the aerodynamic particle size of the powder exiting the device, […]
Characterising the Physical Properties of Spray Dried Powders
The Benefits of Powder Characterisation When developing products containing spray dried powders it is vital that the physical properties of the powders produced are determined. The physical properties of spray dried powders provides important information that can assist during the pre-formulation screening and early process development phases since these properties will have a direct impact […]
Upperton Pharma Solutions launches nasal delivery development platform
5th April 2022 – Press Release Nottingham-based contract development and manufacturing organisation (CDMO), Upperton Pharma Solutions, has launched a unique nasal delivery development platform, UpperNose™, to make it easier and faster for small and mid-sized innovators to access the knowledge and capabilities necessary for the successful development of nasal dosage formulations. Drug developers seeking to […]
Growing Interest in Nasal Drug Delivery
Nasal drug delivery route for small molecules and biologics. Recent trends have seen growing interest in exploiting nasal drug delivery as a means of delivering a wide range of drugs including small molecules and larger biologics for a wide range of indications. The nasal cavity is already a well-established delivery route capable of achieving rapid […]
Upperton Adds New Nasal and Oral Delivery Technologies
January 27th 2022 : Newsletter Upperton is pleased to announce that it has bolstered its nasal and oral delivery capabilities with the addition of a number of new analytical and formulation technologies. Nasal Delivery News – Upperton enhances its analytical capabilities by acquiring next generation nasal particle impaction technology Upperton has acquired the Copley Alberta Idealised […]
Formulation Options in Nasal Drug Delivery
Liquid Delivery Dry Powder Delivery Dry Powder vs Liquid Devices Delivery Considerations FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour Nasal delivery options The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be […]
Nasal Delivery of Therapeutics and Vaccines
Overview of Nasal Delivery Nasal Physiology for Drug Delivery Nasal Delivery Advantages FAQs Nasal Delivery Overview The anatomy and physiology of the nasal cavity creates a number of unique opportunities for the successful delivery of drugs and vaccines. This can be locally, systemically or directly to the central nervous system. This utility has resulted in […]
Key Considerations when Choosing a Device for Dry Powder Nasal Delivery
Nasal Delivery The Nasal Cavity Nasal Devices Patient Profile Target Dose FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour Nasal delivery overview Drug administration via the nasal route can be used as an efficient method of administration for both local and systemic acting drugs. The nasal route […]
Considerations when Developing Dry Powder Formulations for Nasal Locally Delivered Drugs
By 2020, 58% of all therapeutics in development are injectable, 29% oral and 4% inhaled including nasal delivery, and while nasal delivery may not be one of the most explored routes, it has the potential to offer an alternative delivery method for therapeutics with some specific advantages. Nasal delivery of drugs has traditionally been via […]