Spray Dried Biologics

Biologic therapies are transforming the treatment landscape across a wide range of diseases, but their development often comes with significant formulation and stability challenges.

Many proteins, peptides, antibodies and emerging biologic modalities are inherently sensitive, requiring careful handling throughout development, manufacturing and distribution to maintain their integrity and therapeutic performance.

Spray drying has emerged as a powerful formulation technology that can help address these challenges. By converting biologic molecules into carefully engineered dry powders, spray drying can improve stability, support alternative routes of administration and create opportunities for more patient-friendly therapies.

At Upperton, we apply our expertise in complex molecule development, formulation science and particle engineering to support the development of spray dried biologics from early feasibility through to clinical supply manufacture. Working closely with our clients, we design formulation strategies that protect sensitive molecules while delivering the particle characteristics needed to achieve the desired therapeutic outcome.