Manufacturing Clinical Supplies: Planning a First-in-Human Study
What are Clinical Trials? What is a First in Human Study? Proof of Concept FIH Studies Commercial Robust Method FAQs What are Clinical Trials? Clinical trials are one of the most important components of any drug development project, requiring careful planning and extensive funding. Clinical trials are conducted to improve the efficacy and quality of […]
Manufacturing Clinical Supplies: The Role of Placebos and the Challenges they Present
Manufacturing a suitable placebo dosage form presents many unique challenges over and above those required for the active product.
Key Considerations when Choosing a Device for Dry Powder Nasal Delivery
Nasal Delivery The Nasal Cavity Nasal Devices Patient Profile Target Dose FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour Nasal delivery overview Drug administration via the nasal route can be used as an efficient method of administration for both local and systemic acting drugs. The nasal route […]
Considerations when Developing Dry Powder Formulations for Nasal Locally Delivered Drugs
By 2020, 58% of all therapeutics in development are injectable, 29% oral and 4% inhaled including nasal delivery, and while nasal delivery may not be one of the most explored routes, it has the potential to offer an alternative delivery method for therapeutics with some specific advantages. Nasal delivery of drugs has traditionally been via […]
A Tablet Development Journey at Upperton
With the continued expansion of our tablet formulation development services, Upperton currently have a number of tablet dosage form development projects completed or in progress. Theses tablet / solid dosage form projects have encompassed a wide range of development activities from Active Pharmaceutical Ingredient (API) characterisation and feasibility studies through the application of enabling technologies, […]
Stages of Tablet Development: Compression Equipment Overview
Stages of Tablet Compression Equipment Used During Formulation and Process Development Tablets are one of the most popular dosage forms used in the pharmaceutical, nutraceutical and veterinary industries due to their ease of handling and administration, stability, convenient packing options and well-established cost-effective manufacturing processes which produce consistent quality products. Developing a tablet formulation from […]
Formulating Spray Dried Dispersions into Tablets
What Are ASDs? How Are ASDs Produced? Advantages of Spray Drying Challenges in Developing SDDs into Tablets FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour In this article, Upperton interviewed Dr Ian Lafferty, our Chief Technical Officer on the topic of developing spray dried dispersions (SDDs) into […]
Applications and Techniques of Pharmaceutical Granulation
What is Granulation? Wet Granulation Wet Granulation Options Dry Granulation Dry Granulation Options Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour What is Granulation? Granulation has been widely used in the pharmaceutical industry since the 1950s. Whilst the science remains largely identical to that developed over 70 years […]
Tablet Formulation: A General Overview
Tablet Formulation Strategies Solid Dosage Forms Tablet Manufacture Process Tablet Press FAQs Loading the Elevenlabs Text to Speech AudioNative Player… Talk to our experts Virtual Facility Tour Tablets continue to be one of the most popular pharmaceutical dosage forms, as with the right tablet formulation you can achieve: ease of handling and administration for patients, […]
Tablets: A General Overview
Listen to the article Loading the Elevenlabs Text to Speech AudioNative Player… What are Oral Solid Tablets? Examples of Tablets Considerations for Tablet Design FAQs Tablet dosage forms are one of the most popular dosage forms used in the pharmaceutical industry due to their ease of handling and administration for patients, stability, convenient packing options […]